The I-485 filed by your spouse would not be accepted - 回复：would

The I-485 filed by your spouse would not be accepted by USCIS, if it is only based on your I-140.  Since hers was accepted, it must be on the ground of your I-485.  When we put it in another way, she could not have her I-485 accepted if yours has not yet accepted, no matter whether she got your I-140 or not.

As for her I-485, it is granted that she needs none of your sponsorship nor your signature nor your consent.  If you still feel uncomfortable, you may get a divorce and finalize it prior to the approval of your I-485.  If you can't get the divorce soon enough then withdraw your I-485 so as to impact hers negatively, a lose-lose situation.  I am sorry that there is no other way you are capable of messing her I-485 up unfortunately, although you are not forbidden from any attempts. 

Let's talk about your house.  You bought a house, and your wife lives in it with you.  Would you think that “关系紧张， 对生活和工作有负面影响” so you can kick her out? If you spend some time in thinking about the replies you received above, I believe you would finally come to a decision of gentleman.