colorectal oncogenesis in mini-colons ex vivo

Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo

Topobiologically complex mini-colons—which enable the faithful in vitro recapitulation of colorectal cancer tumorigenesis and its environmental determinants—offer the possibility to reduce animal use in a wide range of experimental applications.

• L. Francisco Lorenzo-Martín
• Tania Hübscher
• Matthias P. Lutolf